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DNA Recombination - Methods and Protocols (Hardcover, 2011)
Loot Price: R5,292
Discovery Miles 52 920
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DNA Recombination - Methods and Protocols (Hardcover, 2011)
Series: Methods in Molecular Biology, 745
Expected to ship within 10 - 15 working days
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Homologous recombination is important in various aspects of DNA
metabolism, including damage repair, replication, telomere
maintenance, and meiosis, and yeast genetics has successfully
provided a framework for the mechanism of homologous recombination.
Divided into four convenient sections, DNA Recombination: Methods
and Protocols covers recent techniques that best utilize the
advantages of the yeast system, prescribing to the belief that
yeast will keep serving as a great model organism to study
homologous recombination. Chapters have also been included for such
exceptions as the group of genes involved in recombination that are
found solely in higher eukaryotes, such as BRCA2. And looking
forward, a necessary step in the direction of understanding the
homologous recombination process is to isolate the machine and let
it work in a test tube. Understanding the design by studying the
appearance and behavior of the machinery as a single molecule will
be an important milestone toward understanding the mechanism of
action of the machinery. Techniques covering these topics have also
been included. Written in the successful Methods in Molecular
Biology (TM) series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible protocols, and notes on
troubleshooting and avoiding known pitfalls. Authoritative and
easily accessible, DNA Recombination: Methods and Protocols serves
as an ideal guide to scientists of all backgrounds with its
well-honed methodologies and strives to bring the reader to the
next level of understanding regarding this vital subject.
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