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Coronaviruses - Molecular Biology and Virus-Host Interactions (Paperback, Softcover reprint of the original 1st ed. 1993)
Loot Price: R1,635
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Coronaviruses - Molecular Biology and Virus-Host Interactions (Paperback, Softcover reprint of the original 1st ed. 1993)
Series: Advances in Experimental Medicine and Biology, 342
Expected to ship within 10 - 15 working days
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Coronaviruses represent a major group of viruses of both molecular
biological interest and clinical significance in animals and
humans. During the past two decades, coronavirus research has been
an expanding field and, since 1980, an international symposium was
held every 3 years. We organized the yth symposium for providing an
opportunity to assess important progresses made since the last
symposium in Cambridge (U. K. ) and to suggest areas for future
investigations. The symposium, held in September 1992, in
Chantilly, France, was attended by 120 participants representing
the majOlity of the laboratories engaged in the field. The present
volume collects 75 papers which were presented during the yth
symposium, thus providing a comprehensive view of the state of the
art ofCoronavirology. The book is divided into 7 chapters. The
first chapters gather reports dealing with genome organization,
gene expression and structure-function relationships of the viral
polypeptides. New sequence data about as yet poorly studied
coronaviruses - canine coronavirus CCY and porcine epidemic
diarrhoea virus PEDY - are presented. Increasing efforts appear to
be devoted to the characterization of products of unknown function,
encoded by various open reading frames present in the coronavirus
genomes or delived from the processing of the large polymerase
polyprotein. Due to the extreme size of their genome, the genetic
engineering ofcoronavi\'uses through the production of full length
cDNA clones is presently viewed as an unachievahle task.
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