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Neural Metabolism In Vivo (Hardcover, 2012 ed.)
Loot Price: R5,716
Discovery Miles 57 160
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Neural Metabolism In Vivo (Hardcover, 2012 ed.)
Series: Advances in Neurobiology, 4
Expected to ship within 10 - 15 working days
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From the preface: "Neural Metabolism In Vivo aims to provide a
comprehensive overview of neurobiology by presenting the basic
principles of up-to-date and cutting-edge technology, as well as
their application in assessing the functional, morphological and
metabolic aspects of the brain. Investigation of neural activity of
the living brain via neurovascular coupling using multimodal
imaging techniques extended our understanding of fundamental
neurophysiological mechanisms, regulation of cerebral blood flow in
connection to neural activity and the interplay between neurons,
astrocytes and blood vessels. Constant delivery of glucose and
oxygen for energy metabolism is vital for brain function, and the
physiological basis of neural activity can be assessed through
measurements of cerebral blood flow and consumption of glucose and
oxygen.... This book presents the complex physiological and
neurochemical processes of neural metabolism and function in
response to various physiological conditions and pharmacological
stimulations. Neurochemical detection technologies and quantitative
aspects of monitoring cerebral energy substrates and other
metabolites in the living brain are described under the "Cerebral
metabolism of antioxidants, osmolytes and others in vivo" section.
Altogether, the advent of new in vivo tools has transformed
neuroscience and neurobiology research, and demands
interdisciplinary approaches as each technology could only
approximate a very small fraction of the true complexity of the
underlying biological processes. However, translational values of
the emerging in vivo methods to the application of preclinical to
clinical studies cannot be emphasized enough. Thus, it is our hope
that advances in our understanding of biochemical, molecular,
functional and physiological processes of the brain could
eventually help people with neurological problems, which are still
dominated by the unknowns." -- In-Young Choi and Rolf Gruetter
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