Books > Medicine > Clinical & internal medicine > Haematology
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Bortezomib in the Treatment of Multiple Myeloma (Hardcover, Edition.)
Loot Price: R2,955
Discovery Miles 29 550
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Bortezomib in the Treatment of Multiple Myeloma (Hardcover, Edition.)
Series: Milestones in Drug Therapy
Expected to ship within 10 - 15 working days
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Multiple Myeloma (MM) is the second most common type of blood
cancer, resulting from an overproduction of cancerous
infection-fighting white blood cells, known as plasma cells. Plasma
cells are a crucial part of the immune system responsible for the
production of antibodies. Bortezomib is a promising anticancer drug
targeting the proteasome. This proteasome inhibitor induces cell
stress and apoptosis in the cancer cells. While multiple mechanisms
are likely to be involved, proteasome inhibition may prevent the
degradation of pro-apoptotic factors, permitting activation of
programmed cell death in neoplastic cells dependent upon the
suppression of proapoptotic pathways. This monograph on bortezomib
is a valuable source of information for researchers and clinicians
from the fields of oncology and pharmacology, working either in
academia or the pharmaceutical industry.
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