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Immunopharmacology (Paperback, Softcover reprint of the original 1st ed. 1977)
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Immunopharmacology (Paperback, Softcover reprint of the original 1st ed. 1977)
Series: Comprehensive Immunology, 3
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Immunopharmacology: A New Discipline of Immense Potential Among the
looming triumphs of the biologic revolution is the rapidly
developing understanding of the mechanisms of bodily defense. In
the short span of 35 years, knowledge of immunologic machinery has
progressed from crudest description to major understanding in
cellular and molecular terms. Antibodies, immunoglobulins, and the
complement system have been almost completely defined in detailed
molecular terms. Organs, like thymus, spleen and lymph nodes-so
long enigmatic black boxes-are beginning to be understood not only
in cellular terms but in molecular, physiologic, and endocrinologic
terms. With this surging new information about the immune system
comes the possi bility of developing a pharmacology which can
modulate and control immunologic functions. Immunopharmacology most
broadly conceived must address (1) control of development and
function of the cellular components of the immunologic appara tus;
(2) facilitation and suppression of function of the immunologically
competent cells of the several subclasses, like T helpers,
suppressors, and effectors, and B effectors and suppressors; (3)
manipulation and repair of the major biologic amplifi cation
systems, e. g., the complement system and kinin-kallikrein system,
and (4) utilization, modulation, and inhibition of the galaxy of
molecules generated by T lymphocytes, the lymphokines. This new
pharmacology must deal with the funda mental effector mechanisms of
immunity, namely inflammation, phagocytosis, vascular reactivity,
and blood coagulation. Furthermore, immunopharmacology must address
and manipulate cell-cell communication and interaction, so vital to
control of the immunological apparatus."
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
Comprehensive Immunology, 3 |
Release date: |
November 2012 |
First published: |
1977 |
Editors: |
J. Hadden
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Dimensions: |
254 x 203 x 23mm (L x W x T) |
Format: |
Paperback
|
Pages: |
423 |
Edition: |
Softcover reprint of the original 1st ed. 1977 |
ISBN-13: |
978-1-4615-7251-0 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Diseases & disorders >
Immunology >
General
|
LSN: |
1-4615-7251-7 |
Barcode: |
9781461572510 |
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