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Neuroinflammatory Mechanisms in Alzheimer's Disease - Basic and Clinical Research (Hardcover)
Loot Price: R2,482
Discovery Miles 24 820
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Neuroinflammatory Mechanisms in Alzheimer's Disease - Basic and Clinical Research (Hardcover)
Series: Progress in Inflammation Research
Expected to ship within 12 - 17 working days
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Twenty years ago, the idea that Alzheimer's disease (AD) involved
any sort of inflammatory or immune component seemed implausible.
Now, there are hundreds of laboratories world-wide that are
pursuing basic research in this area, and multi-site clinical
trials are underway. How this dramatic sea-change came about is
made clear in this book, both through overviews of the field and
through focused papers on specific topics of recent interest.
Complement, cytokines and the complex host of other acute phase
reactants are covered, as are summaries of many epidemiologic and
clinical-pathological findings. Written by established
investigators who have led neuroinflammatory research for two
decades, this volume particularly emphasizes correlations between
inflammatory phenomena in the brains of AD patients with findings
of the "classic" approach, such as pathophysiologic effects of
amyloid b peptide. The book documents and synthesizes earlier and
recent findings in AD to help a broad range of scientists in
gaining a broader and more comprehensive knowledge of the
complexities AD presents. In addition, many of the concepts and
results that have emerged from AD inflammation research may have
implications for other neurologic disorders that involve
inflammatory components, including multiple sclerosis and stroke.
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