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Prostate Cancer and Bone Metastasis (Paperback, Softcover reprint of the original 1st ed. 1992)
Loot Price: R1,577
Discovery Miles 15 770
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Prostate Cancer and Bone Metastasis (Paperback, Softcover reprint of the original 1st ed. 1992)
Series: Advances in Experimental Medicine and Biology, 324
Expected to ship within 10 - 15 working days
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The biology of solid tumor metastasis has been the subject of
significant scientific and clinical interest for years and while
experimental evidence reveals that metastasis is not solely a
random event, very little is known about the biology of metastasis
originating from prostate cancer. This is in spite of the fact that
the majority of prostate cancer patients die with metastatic
lesions to the bone. Progress in understanding this most important
aspect of prostate cancer has been hampered by the lack of suitable
animal models and an inability to accurately quantify bone
metastases and their responses to therapy. Over the past decade,
scientists in Japan and the United States have steadily advanced
our understanding of the cellular, molecular and immunologic
biology of primary and disseminated prostate cancer. It is this
body of new information, combined with advances in imaging
techniques and prostate cancer tumor markers, that prompted the
need for an in-depth assessment of bone metastasis of prostate
cancer. Accordingly, on December 12, 1990, a group of basic and
clinical investigators from Japan and the United States convened in
Gotenba, Japan, to hold the first conference devoted solely to the
basic biology and clinical aspects of bone metastases originating
from prostate cancer. The cross-fertilization of ideas that was
fostered through in-depth discussion of technological advances
among various basic and clinical disciplines not only further
advanced our understanding of prostate metastases to the bone, but
suggested approaches for precise quantitative assessment of these
lesions and their treatment.
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