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The Double [3+2] Photocycloaddition Reaction (Hardcover, 2011)
Loot Price: R2,950
Discovery Miles 29 500
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The Double [3+2] Photocycloaddition Reaction (Hardcover, 2011)
Series: Springer Theses
Expected to ship within 10 - 15 working days
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Jason Woolford's thesis describes for the first time, a double
[3+2] photocycloaddition of alkenes onto aromatic rings. Modern
synthetic chemistry relies on the ability of researchers to uncover
new and more efficient ways of creating highly complex structures.
This work describes a novel, environmentally friendly photochemical
step that converts in one pot, trivial starting materials into
otherwise difficult to construct fenstrane frameworks. The rigid
cores of these frameworks have significant potential in drug
design. Moreover, the novelty of this work overtakes many other
methods for the creation of chiral centres. No less than seven
chiral centres are created in the photochemical step together with
the formation of four carbon-carbon bonds and multifused rings.
Jason's innovative work has been the subject of several
publications in peer-reviewed journals.
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