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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Biofilms, Infection, and Antimicrobial Therapy (Paperback)
Loot Price: R1,991
Discovery Miles 19 910
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Biofilms, Infection, and Antimicrobial Therapy (Paperback)
Expected to ship within 12 - 17 working days
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Rather than existing in a planktonic or free-living form, evidence
indicates that microbes show a preference for living in a sessile
form within complex communities called biofilms. Biofilms appear to
afford microbes a survival advantage by optimizing nutrition,
offering protection against hostile elements, and providing a
network for cell-to-cell signaling and genetic exchange. Biofilms,
Infection, and Antimicrobial Therapy provides an in-depth
exploration of biofilms, offering broad background information, as
well a detailed look at the serious concerns to which
biofilm-associated infections give rise. Prosthetic device
infections, such as those involving artificial heart valves,
intravascular catheters, or prosthetic joints, are prime examples
of biofilm-associated infections. With the increasing use of such
devices in the modern practice of medicine, the prevalence of these
infections is expected to increase. Unfortunately, one of the most
troubling characteristics of microbes found in biofilms is a
profound resistance to antimicrobial agents. As biofilm-associated
infections are particularly difficult to treat, they result in
significant mortality, morbidity, and increased economic burden.
Clearly, a better understanding of the pathogenesis of these
infections and improved means for prevention and treatment are
urgently needed! InBiofilms, Infection, and Antimicrobial Therapy,
Drs Pace, Rupp, and Finch assemble the contributions of more than
50 of the world's leading authorities on microbial biofilms who
present recent findings on antibacterial tolerance and bacterial
persistence associated with biofilms and discuses the implications
of those findings with regard to human health. They explore the
molecular mechanisms of bacterial adherence, biofilm formation,
regulation of biofilm maintenance, and cell-to-cell communication
and present the latest information on various treatment protocols
that should aid physicians in the treatment o
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