Rhim and Kremer s state-of-the-art volume on "Human Cell
Transformation: Role of Stem Cells and the Microenvironment"
highlights the latest findings on the current state of human cell
transformation model systems and provides the insight into the
molecular and cellular changes involved in the conversion of normal
cells to neoplastic cells.
Chapters cover all recently developed novel human cell models.
In addition, the rapidly growing fields of knowledge regarding not
only stem cells in cancer progression, but also the role of the
microenvironments in human carcinogenesis are discussed. A wealth
of topics is presented including:
. Derivation of epithelial, fibroblastic, and hematopoietic "in
vitro" model systems
. Oncogenes
. Tumor suppressor genes
. Viral transformation
. "In vitro" model systems for viral, chemical and radiation
carcinogenesis
. Cell aging
. The multistep nature of human carcinogenesis. The role of stem
cells and the microenvironment in tumorigenesis
. The genes involved in multistep carcinogenesis
Unique in both scope and focus devoted solely to human cell
transformation systems "Human Cell Transformation: Role of Stem
Cells and the Microenvironment" provides unparalleled, in-depth
coverage for cancer researchers, cell and molecular biologists,
hematologists, virologists, and workers in related fields.
Essential reading for everyone who needs to be kept up-to-date
in this fast-paced area
Features
O Multistep models
O Breast cancer/Stem cells
O Prostate cancer/Stem cells
O Multistep / Genes"
General
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