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Rheumatoid Arthritis - Recent Research Advances (Paperback, Softcover reprint of the original 1st ed. 1992)
Loot Price: R4,524
Discovery Miles 45 240
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Rheumatoid Arthritis - Recent Research Advances (Paperback, Softcover reprint of the original 1st ed. 1992)
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Total price: R4,544
Discovery Miles: 45 440
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Many advances have occurred in the last 5 years especially in
understanding genetic susceptibility factors, the role of immune
response in chronic arthritis and the relationship between cellular
processes that underlie inflammation and tissue damage. All these
are dealt with in depth in the individual contributions. Genetics
studies included illustrate how studies of HLA genes and genes
controlling the autoantibody repertoire may be involved.
Environmental factors are believed to be important and studies both
in humans and in experimental models on the role of viral and
bacterial agents are covered. The fascinating relationship between
microbes, dysregulated immune responses and oncogenes are also
examined. Since autoimmunity is the key aspect of the immunological
response in rheumatoid arthritis, the role of antigens is
re-examined as is the part played by immune T and B cells. New
areas of clinical application of basic science is well presented in
this book, forexample, in examining how markers of cartilage
destruction may become important in monitoring disease activity. A
chapter reviewing possible future novel therapies is included.
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