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Books > Science & Mathematics > Biology, life sciences > Microbiology (non-medical)
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Recent Trends in Human and Animal Mycology (Hardcover, 1st ed. 2019)
Loot Price: R4,260
Discovery Miles 42 600
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Recent Trends in Human and Animal Mycology (Hardcover, 1st ed. 2019)
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Fungal pathogens pose an on-going and serious threat for
poikilotherms and homeotherms, and can cause a broad spectrum of
diseases ranging from innocuous to life-threatening. In addition,
long-term exposure to some mycotoxigenic moulds can lead to
mycotoxicoses in human and animals. Given the expanding population
of immune compromised hosts, the list of fungal opportunists grows
longer every year. Moreover, antifungal resistance, drug-related
toxicity and our limited arsenal of antifungals have exacerbated
the situation. To address these problems, strategies such as the
identification of novel targets, use of the structure-activity
relationship in rational drug design, development of new
formulations, modification of existing antifungals to combat
resistance, and bioavailability enhancement are called for. For the
reader's convenience, this book has been divided into three
sections. The first six chapters of Section I provide a timely
review of mycoses, from endemic to cosmopolitan and from
generalized to specific, while both chapters of Section II focus on
risks associated with mycotoxins. In closing, the two chapters of
Section III describe potential antifungal leads and drug candidates
based on phytochemicals and coumarin scaffold.
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