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Human Retroviral Infections - Immunological and Therapeutic Control (Paperback, Softcover reprint of the original 1st ed. 2002) Loot Price: R4,407
Discovery Miles 44 070
Human Retroviral Infections - Immunological and Therapeutic Control (Paperback, Softcover reprint of the original 1st ed....

Human Retroviral Infections - Immunological and Therapeutic Control (Paperback, Softcover reprint of the original 1st ed. 2002)

Kenneth E. Ugen, Mauro Bendinelli, Herman Friedman

Series: Infectious Agents and Pathogenesis

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Loot Price R4,407 Discovery Miles 44 070 | Repayment Terms: R413 pm x 12*

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The discovery of the human T cell leukemia virus type I in the late 1970s heralded a new era in retrovirology. For the first time, it was demonstrated that a retrovirus could play a role in the development of a human disease, in this case adult T cell leukemia (ATL). Several years later, the acquired immunodeficiency syndrome (AIDS) epidemic began, and it was dem- strated that a retrovirus, originally designated the human T cell lymp- tropic virus type 3, was the causal agent of this syndrome. This virus, later named the human immunodeficiency virus type 1 (HIV-1), has since been extensively studied in terms of its pathogenesis as well as its ability to elicit immune responses. In that time, a tremendous amount of information has been obtained about the virus. Although recent drug regimens have been useful in significantly lowering viral loads and perhaps maintaining an asymptomatic state among individuals infected with HIV-1, an established "cure" for AIDS eludes us. In addition, the effective drug therapies are very expensive, and are not available to infected people in the third world, where greater than 90% of new infections occur. Furthermore, the development of viral resistance against the drug therapies is an additional concern. Despite extensive study, no effective vaccine has been developed. One of the problems in developing an effective vaccine against HIV-1 is the ability of the virus, particularly in the immunogenic envelop glycoprotein, to undergo amino acid hypervariability.

General

Imprint: Springer-Verlag New York
Country of origin: United States
Series: Infectious Agents and Pathogenesis
Release date: March 2013
First published: 2002
Editors: Kenneth E. Ugen • Mauro Bendinelli • Herman Friedman
Dimensions: 235 x 155 x 21mm (L x W x T)
Format: Paperback
Pages: 368
Edition: Softcover reprint of the original 1st ed. 2002
ISBN-13: 978-1-4757-8168-7
Categories: Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy > General
Books > Medicine > Other branches of medicine > Pathology > Gross pathology
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > General
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN: 1-4757-8168-7
Barcode: 9781475781687

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