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Advances in Swine in Biomedical Research - Volume 2 (Paperback, Softcover reprint of the original 1st ed. 1996)
Loot Price: R1,549
Discovery Miles 15 490
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Advances in Swine in Biomedical Research - Volume 2 (Paperback, Softcover reprint of the original 1st ed. 1996)
Expected to ship within 10 - 15 working days
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Donate to Against Period Poverty
Total price: R1,569
Discovery Miles: 15 690
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Similarities in structure and function between pigs and human
beings include size, feeding patterns, digestive physiology,
dietary habits, kidney structure and function, pulmo nary vascular
bed structure, coronary artery distribution, propensity to obesity,
respiratory rates, tidal volumes and social behaviors. Since the
pig is an omnivore, it provides an adaptable model to evaluate
chronic and acute exposures to xenobiotics such as alcohoL
caffeine, tobacco, food additives and environmental pollutants.
Swine have been used successfully as models to evaluate alcoholism,
diabetes, absorption, digestion, total paren teral nutrition, organ
transplantation, atherosclerosis, exercise, hypertension.
hemorrhagic hypotension, melanoma, gingivitis, obstructive and
reflux nephropathy. osteochondrosis. dermal healing and septic
shock. A severe and worsening shortage of organs and tissues for
transplantation in patients with severe organ failure has
encouraged the consideration of inter species or xenotransplan
tation. In developing programs toward this end, the pig generally
is viewed as the preferred donor because of its size, physiology
and availability. The pig harbors relatively few diseases which
could be transmitted inadvertently to human patients. The ability
to genetically modify swine to ameliorate the consequences of the
human immune response offers a further significant advantage.
Another important consideration for an animal model is that basic
biologic back ground information be available for investigators to
design future prospective studies."
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