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Histological Typing of Kidney Tumours - In Collaboration with L. H. Sobin and Pathologists in 6 Countries (Paperback, 2nd ed.)
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Histological Typing of Kidney Tumours - In Collaboration with L. H. Sobin and Pathologists in 6 Countries (Paperback, 2nd ed.)
Series: WHO. World Health Organization. International Histological Classification of Tumours
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This classification is based primarily on the microscopic charac-
teristics of tumours and, therefore, is concerned with morpho-
logically identifiable cell types and histological patterns, as
seen with conventional light microscopy. The term tumours is used
synonymously with neoplasm. The phrase tumour-like is applied to
lesions which resemble neo- plasms, clinically or morphologically,
but do not behave biologi- cally in a neoplastic manner. They are
included in this classifica- tion because they give rise to
problems in differential diagnosis and because of the unclear
borderline between neoplasms and certain non-neoplastic lesions.
Synonyms are listed only if they have been used widely, or if they
are considered to be helpful to the understanding of the lesion. In
such cases, the preferred term is given first, followed by the
synonym. Although the emphasis of this classification is on
histological typing, in the examination of kidney tumours,
consideration should be given to the degree of cellular anaplasia,
the extent of local spread, vascular and lymphatic invasion, and
the occur- rence of metastasis. The scheme of histological grading
suggested here is as fol- lows: Grade I applies to the tumours that
have the least degree of cellular anaplasia compatible with a
diagnosis of malignancy; . grade II! applies to tumours with the
most severe degrees of cel- lular anaplasia; and grade I! applies
to those tumours in be- tween. This scheme is applicable to the
carcinomas of the renal parenchyma and pelvis.
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