Polymer translocation occurs in many biological and
biotechnological phenomena where electrically charged polymer
molecules move through narrow spaces in crowded environments.
Unraveling the rich phenomenology of polymer translocation requires
a grasp of modern concepts of polymer physics and polyelectrolyte
behavior. Polymer Translocation discusses universal features of
polymer translocations and summarizes the key concepts of
polyelectrolyte structures, electrolyte solutions, ionic flow,
mobility of charged macromolecules, polymer capture by pores, and
threading of macromolecules through pores.
With approximately 150 illustrations and 850 equations, the
book:
- Avoids heavy mathematics
- Uses examples to illustrate the richness of the phenomenon
- Introduces the entropic barrier idea behind polymer
translocation
- Outlines conceptual components necessary for a molecular
understanding of polymer translocation
- Provides mathematical formulas for the various quantities
pertinent to polymer translocation
The challenge in understanding the complex behavior of
translocation of polyelectrolyte molecules arises from three
long-range forces due to chain connectivity, electrostatic
interactions, and hydrodynamic interactions. Polymer Translocation
provides an overview of fundamentals, established experimental
facts, and important concepts necessary to understand polymer
translocation. Readers will gain detailed strategies for applying
these concepts and formulas to the design of new experiments.
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