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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Cancer and IgE - Introducing the Concept of AllergoOncology (Hardcover, 2010 ed.)
Loot Price: R4,618
Discovery Miles 46 180
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Cancer and IgE - Introducing the Concept of AllergoOncology (Hardcover, 2010 ed.)
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Erika Jensen-Jarolim and Manuel L. Penichet 1. 1 Background
Infectious diseases, being the major burden in the history of
mankind worldwide th until the beginning of the 20 century, were
important triggers in the understanding of immunological
mechanisms. In contrast to infectious diseases, reports of all-
gies and cancers were less common, but increased tremendously
within the last century. Based on the US mortality data of the
National Center for Health Statistics, Centers for Disease Control
and Prevention 2009, a recent report from the American Cancer
Society indicated that the number of cancer deaths increased
approximately from 100,000 to 550,000 per year between 1930 and
2006, paralleling the increase of the total population during this
period. Leading causes of death from cancer are lung and bronchus
cancer, in men prostate cancer, and in women breast c- cer [1, 2].
Normalization to population size shows that the cancer death rate
for most malignancies has been generally stable, although the
mortality rate of certain malignancies, such as lung and bronchus
cancer, has increased over the last 50 years [1-3]. In allergy, the
situation is less clear, because for the time period around the
turn of th the 19 century, only imprecise information is available.
However, within the last 30 years the incidences of allergies has
doubled not only in industrial countries, but in developing
countries as well [4].
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