The volumes in this authoritative series present a
multidisciplinary approach to modeling and simulation of flows in
the cardiovascular and ventilatory systems, especially multiscale
modeling and coupled simulations. The cardiovascular and
respiratory systems are tightly coupled, as their primary function
is to supply oxygen to and remove carbon dioxide from the body's
cells. Because physiological conduits have deformable and reactive
walls, macroscopic flow behavior and prediction must be coupled to
nano- and microscopic events in a corrector scheme of regulated
mechanisms. Therefore, investigation of flows of blood and air in
physiological conduits requires an understanding of the biology,
chemistry, and physics of these systems together with the
mathematical tools to describe their functioning.
The present volumeis devoted to cellular events that allow
adaptation to environmental conditions, particularly
mechanotransduction.It begins with cell organization and a survey
of cell types in the vasculature and respiratory tract. It then
addresses cell structure and functions, especially in interactions
with adjoining cells and matrix."
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