Multivariate analysis of the multi-component analytical profiles
of carefully collected biofluid and/or tissue biopsy specimens can
provide a 'fingerprint' of their biomolecular/metabolic status.
Therefore, if applied correctly, valuable information regarding
disease indicators, disease strata and sub-strata and disease
activities can be obtained.
This exemplary new book highlights applications of these
techniques in the areas of drug therapy and toxicology, cancer,
obesity and diabetes, as well as outlining applications to
cardiovascular, infectious, inflammatory and oral diseases in
detail. The book gives particular reference to cautionary measures
that must be applied to the diagnosis and classification of these
conditions or physiological criteria. Comprehensively covering a
wide range of topics, of particular interest is the focus on
experimental design and 'rights and wrongs' of the techniques
commonly applied by researchers, and the very recent development of
powerful 'Pattern Recognition' techniques.
The book provides a detailed introduction to the area,
applications and common pitfalls of the techniques discussed before
moving into detailed coverage of specific disease areas, each
highlighted in individual chapters. This title will provide an
invaluable resource to Medicinal chemists, Biochemists and
toxicologists working in industry and academia.
General
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