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Books > Medicine > Clinical & internal medicine > Haematology
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Role of Regucalcin in Cell Homeostasis & Disorder (Hardcover)
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Role of Regucalcin in Cell Homeostasis & Disorder (Hardcover)
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Cyclic AMP was a major molecule of interest, which played an
important role as second messenger, contributing to signal
transduction in the regulation of cellular function by peptide
hormones. Afterwards, calmodulin and protein kinase C were
discovered as modulator proteins of intracellular calcium signaling
in hormonal action. After that, manifold proteins and their related
molecules were demonstrated to participate in novel signaling
pathways related to various cytokines in different types of cells.
The author of this book discovered a novel protein known as
regucalcin, which suppresses manifold signaling pathways related to
transcription activity. After subsequent studies, regucalcin has
been established to play a pivotal role in maintaining cell
homeostasis and protecting it from disorders in various types of
cells and tissues. This book will provide information regarding
regucalcin that plays a pivotal role in cell homeostasis and
disorder. This book is composed of eighteen chapters. These
chapters include the following content: the discovery of regucalcin
(Chapter One); chemical property and structure of regucalcin
(Chapter Two); the regucalcin gene and its translational regulation
(Chapter Three); the role of regucalcin in intracellular calcium
homeostasis (Chapter Four); the role of regucalcin in cell nuclear
function (Chapter Five); the role of regucalcin in protein
synthesis and proteolysis (Chapter Six); the suppressive role of
regucalcin in cell proliferation (Chapter Seven); how regucalcin
protects apoptotic cell death (Chapter Eight); the protective role
of regucalcin in oxidative stress (Chapter Nine); the involvement
of regucalcin in liver metabolic disorder (Chapter Ten); the role
of regucalcin in kidney cell homeostasis: involvement in renal
failure (Chapter Eleven); the role of regucalcin in heart calcium
signaling: insight into cardiac disorder (Chapter Twelve); the role
of regucalcin in brain calcium homeostasis: disorder with aging
(Chapter Thirteen); the role of regucalcin in bone homeostasis and
osteoporosis (Chapter Fourteen); the role of regucalcin in lipid
metabolism and diabetes (Chapter Fifteen); the role of regucalcin
as a suppressor protein in carcinogenesis (Chapter Sixteen); the
clinical aspects of regucalcin as a biomarker for disease (Chapter
Seventeen); and conclusive remarks (Chapter Eighteen). This book
will provide information regarding regucalcin and its pivotal role
in cell homeostasis and disorder.
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