Colorectal cancer is the third most commonly diagnosed condition in
oncology, affecting around 1.23 million individuals per year,
according to recent statistics. Of these patients, about 50% will
develop liver metastases and approximately 20% will present a stage
IV disease at diagnosis. These statistics make colorectal liver
metastases (CLM) an issue of major importance in current oncology.
The area of CLM is subject to great and continuous advances, as its
pathophysiologic mechanisms are better understood and more
therapeutic and surgical options are developed. Consequently, all
professionals involved with the diagnosis, treatment and follow up
of CLM should be kept up to date with the latest advances on the
field, to provide high standard medical care to their patients.
This book is designed to present the state-of-the-art in CLM
management and, in doing so, to review the current evidence on CLM,
discussing all important topics in the field. Coverage is broad and
comprehensive, encompassing introductory topics (history,
definitions, epidemiology, etc.), basic science subjects (molecular
biology, genetics, dissemination process, etc.) and practical
clinical topics (tumor behavior, diagnosis, drug therapy, radiation
therapy, surgery, ablation, multidisciplinary teams, etc.).
Although comprehensive on the coverage and selection of topics,
each chapter is concise and objective, dissecting topics in a
practical and direct format. Evidences and recommendations are
included. Chapters display a brief introduction of the common
knowledge, go straight to the detailed revision of the most recent
years of the literature, and end with practical closing
observations. This book is a tool for professionals (general and
cancer surgeons, HPB surgeons, clinical oncologists,
gastroenterologists and medical residents) and interns who search
for a qualified and reader friendly revision on topics concerning
Colorectal Cancer Liver Metastases.
General
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