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Evidence-biased Antidepressant Prescription - Overmedicalisation, Flawed Research, and Conflicts of Interest (Hardcover, 1st ed. 2022)
Loot Price: R3,543
Discovery Miles 35 430
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Evidence-biased Antidepressant Prescription - Overmedicalisation, Flawed Research, and Conflicts of Interest (Hardcover, 1st ed. 2022)
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This book addresses the over-prescribing of antidepressants in
people with mostly mild and subthreshold depression. It outlines
the steep increase in antidepressant prescription and critically
examines the current scientific evidence on the efficacy and safety
of antidepressants in depression. The book is not only concerned
with the conflicting views as to whether antidepressants are useful
or ineffective in various forms of depression, but also aims at
detailing how flaws in the conduct and reporting of antidepressant
trials have led to an overestimation of benefits and
underestimation of harms. The transformation of the diagnostic
concept of depression from a rare but serious disorder to an
over-inclusive, highly prevalent but predominantly mild and
self-limiting disorder is central to the books argument. It
maintains that biological reductionism in psychiatry and
pharmaceutical marketing reframed depression as a brain disorder,
corroborating the overemphasis on drug treatment in both research
and practice. Finally, the author goes on to explore how
pharmaceutical companies have distorted the scientific literature
on the efficacy and safety of antidepressants and how patient
advocacy groups, leading academics, and medical organisations with
pervasive financial ties to the industry helped to promote
systematically biased benefit-harm evaluations, affecting public
attitudes towards antidepressants as well as medical education,
training, and practice.
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