"Corynebacterium glutamicum "was discovered in Japan in 1956 as
a natural glutamate producer. Its microbial factory qualities, such
as its physiological plasticity and robust catalytic
functionalities, have since facilitated the development of
efficient production processes for amino acids, nucleotides and
vitamins.
This monograph illustrates how the information gleaned from
complete genome sequencing allows the rational engineering of the
entire cellular metabolism and how systems biology permits the
further optimization of "C. glutamicum" as a biocatalyst. Aspects
of gene regulation, metabolic pathways, sugar uptake, protein
secretion, cell division and biorefinery applications highlight the
enormous biotechnological and biorefinery potential. "
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