While patients with metastatic renal cell carcinoma (mRCC) are now
living longer with improved quality of life, the success of novel
therapies for mRCC has created challenges for practicing
oncologists. Many patients who initially respond to targeted
therapies ultimately develop progressive disease due to acquired
resistance to these agents. Additionally, some patients do not
respond at all to any of the currently approved targeted agents,
underscoring the need for continued and concerted efforts to
identify other relevant targets and pursue alternative therapeutic
strategies. Part of the Oxford American Oncology Library, Renal
Cell Carcinoma is a concise handbook that addresses the complex
management of patients with mRCC. The book begins with a review of
the epidemiology, pathology, and biology of renal cell carcinoma
followed by chapters on specific targeted therapies and managing
complications. The final chapters discuss supportive and
integrative care and emerging therapies.
General
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