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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology
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Nucleic Acids in Immunology - Proceedings of a Symposium Held at the Institute of Microbiology of Rutgers, The State University (Paperback, Softcover reprint of the original 1st ed. 1968)
Loot Price: R4,481
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Nucleic Acids in Immunology - Proceedings of a Symposium Held at the Institute of Microbiology of Rutgers, The State University (Paperback, Softcover reprint of the original 1st ed. 1968)
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Two fields have played a leading role in biomedical research in
recent years, the biochemistry of nucleic acids and immunology.
Yet, with the exception of those aspects which have been concerned
with antibody synthesis as an example of protein synthesis, there
was until recently a lack of direct association between the two
fields. Until quite recently the antigenicity of nucleic acids was
still in doubt and indeed represented a controversial subject.
Also, the exact role of the various nucleic acids in various stages
of antibody synthesis was uncertain. These skepticisms and
uncertainties disappeared rapidly in the last few years. New experi
mental approaches brought the realization that nucleic acids, under
appropriate conditions, are indeed immunogenic, and that the
resulting antibodies can furnish new tools for the exploration of
the mplecular structure of the all-important family of nucleic acid
molecules. ' At the same time, the recognition of the antigenicity
of nucleic acids brought a new level of understanding to certain
auto-immune diseases and pro vided new material for the exploration
of the role of a carrier in immune responses. Side by side with
this development was the almost explosive development of new
experimental approaches and new ideas pertaining to the problem of
antibody formation. Nucleic acids in their various forms were
recognized as playing an expected major role in the activation of
antibody-forming cells. Perhaps less to be expected was the role
they can playas non-specific stimulators of antibody formation.
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