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Orphan G Protein-Coupled Receptors and Novel Neuropeptides (Hardcover, 2008 ed.)
Loot Price: R5,444
Discovery Miles 54 440
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Orphan G Protein-Coupled Receptors and Novel Neuropeptides (Hardcover, 2008 ed.)
Series: Results and Problems in Cell Differentiation, 46
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Over the last decade it has been shown that orphan G
protein-coupled receptors (GPCRs) can be used as targets to
discover novel neuropeptides. A dozen neuropeptides have been
identified through this approach. Each of these neuropeptides has
opened new doors for our understanding of fundamental physiological
or behavioral responses. For example the orexins, MCH and ghrelin
carry fundamental roles in regulating food intake while
neuropeptide S, neuromedin S, the prokineticins and the orexins are
major players in modulating sleep and circadian rhythms. The
chapters of this book review the latest research in the field, most
of them are written by the original discoverers of the respective
novel neuropeptide. Emphasis is set not only on their discovery but
also on their functional significance. Since many of these
neuropeptides are part of drug discovery programs, this book
impacts academic as well as pharmaceutical research. Written for:
Neurobiologists, endocrinologists, pharmaceutical companies
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