These proceedings contain selected contributions from the
participants to the Fourth International Symposium on Dendritic
cells that was held in Venice (Lido) Italy, from Oc tober 5 to 10,
1996. The symposium was attended by more than 500 scientists coming
from 24 different countries. Studies on dendritic cells (DC) have
been greatly hampered by the difficulties in preparing sufficient
cell numbers and in a reasonable pure form. At this meeting it has
been shown that large quantities of DC can be generated from
precursors in both mice and humans, and this possibility has
enormously encouraged studies aimed to characterize DC physiology
and DC-specific genes, and to employ DC therapeutically as
adjuvants for im munization. The possibility of generating large
numbers of autologous DC that can be used in the manipulation of
the immune response against cancer and infectious diseases has
tremendously boosted dendritic cell research and the role of DC in
a number of medi cal areas has been heatedly discussed."
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