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STM and AFM Studies on (Bio)molecular Systems: Unravelling the Nanoworld (Paperback, Softcover reprint of hardcover 1st ed. 2008)
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STM and AFM Studies on (Bio)molecular Systems: Unravelling the Nanoworld (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Series: Topics in Current Chemistry, 285
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The invention of scanning tunneling microscopy (STM) in 1981 [1]
and later
atomicforcemicroscopy(AFM)in1986[2]facilitatedbreakthroughsinvarious
disciplinesofsciencesuchaschemistry,physicsandbiology,andtrulyboosted
the development of nanoscience and nanotechnology. These two
techniques made it possible to achieve a detailed understa- ing of
chemical and biological systems as well as phenomena across
multiple lengthscales, and in particular downto thesub-nanometer
scale. In fact STM and AFM are not simply microscopy tools, but
they are also extremely useful techniques tochemistand biochemists.
Forexample AFMandSTMoffers-
theticchemiststhechancetoobservethemoleculestheyhavesynthesized,how
theymoveand dance onasurface,howtheyrecognizeand communicate with
each other, thus making it possible to cast new light onto the
molecular int- actions[3].
Alongsidetheircapabilityofgeneratingartisticthree-dimensional
pictures with nanoscale resolution, they also allowed the study of
molecular based architectures beyond imaging, providing
quantitative insight into va- ous physico-chemical properties [4]
For instance, by manipulating molecules individually it is possible
to bestow information onto their mechanical pr- erties
andtoperformconstructionsonthenanoscale. In thelastfewyears the
application of AFM and STM to study molecular systems in various
envir- ments (e. g. , liquid, gas, vacuum) is paving the way
towards the unraveling of complex characteristics and phenomena of
nanostructured (bio)systems. Inthisvolumewehaveselected
afewofthemostrelevantexamplesofAFM and STM based experiments on
(bio)molecular based systems, which offer not only a close look
into the nanoworld but also provide quantitative insight into
various properties of molecular and polymeric systems, and
ultimately highlight some technologicallyrelevant applications. I
was delighted and felt privileged to work with an outstanding group
of contributingauthors:Itrulythankthemforalltheirefforts.
Iamalsograteful to Dr. Marion Hertel and Birgit Kollmar-Thoni for
their invitation to edit this volume and for their assistance.
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