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Books > Science & Mathematics > Biology, life sciences > Molecular biology
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Inflammation Protocols (Hardcover, 2003 ed.)
Loot Price: R3,082
Discovery Miles 30 820
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Inflammation Protocols (Hardcover, 2003 ed.)
Series: Methods in Molecular Biology, 225
Expected to ship within 10 - 15 working days
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Inflammation has been described as the basis of many pathologies of
human disease. When one considers the updated signs of
inflammation, they would be vasodilation, cell migration, and, in
the case of chronic inflam- tion, cell proliferation, often with an
underlying autoimmune basis. Gen- ally, inflammation may be divided
into acute, chronic, and autoimmune, - though the editors believe
that most, if not all, chronic states are often the result of an
autoimmune response to an endogenous antigen. Thus, a proper
understanding of the inflammatory basis may provide clues to new
therap- tic targets not only in classical inflammatory diseases,
but atherosclerosis, cancer, and ischemic heart disease as well.
The lack of advances in classical inflammatory diseases, such as
rh- matoid arthritis, may in part arise from a failure to classify
the disease into different forms. That different forms exist is
exemplified in patients with d- fering responses to existing
antiinflammatory drugs, ranging from nonresponders to very positive
responders for a particular nonsteroidal an- inflammatory drug
(NSAID). Though researchers have progressively unr- eled the
mechanisms, the story is far from complete. It should also be noted
that the inflammatory response is part of the innate immune
response, or to use John Hunter's words in 1795, "inflammation is a
salutary response." That may be applied in particular to the
defensive response to invading micro- ganisms.
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