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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Toxicology (non-medical)
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The Illustrated Dictionary of Toxicologic Pathology and Safety Science (Hardcover)
Loot Price: R6,894
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The Illustrated Dictionary of Toxicologic Pathology and Safety Science (Hardcover)
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There has been a growing interest in toxicologic pathology,
especially as related to its impact on the safety assessment of
pharmaceuticals and chemicals, and in drug development. Thus, there
is a growing need for an Illustrated Dictionary of Toxicology
Pathology and Safety Science (IDTP) that this dictionary aims to
fill. The language of toxicologic pathology may be less familiar to
a broad range of safety scientists, especially those involved in
the safety evaluation of pharmaceuticals and chemicals. The IDTP
format provides the brevity and clarity that the user is not likely
to receive in a textbook, even if adequately indexed. With the
inclusion of descriptions for terms used in toxicology, drug
metabolism/pharmacokinetics, and regulatory science, the scope of
the IDTP is considerably broadened and decidedly unique in its
appeal to all safety scientists. With over 800 photos and
illustrations to provide visual context,* an important aim of the
IDTP is to present pathological changes as reference examples for
terminology, nomenclature, and term descriptions for the entry
entry-level as well as seasoned toxicologic pathologist. It will
also aid students and non-pathology specialists such as study
directors, senior toxicology report reviewers, scientific
management of contract research organizations, regulatory agencies,
and drug development companies to better understand the biological
significance of tissue changes. The IDTP provides a single
reference volume for these users to further their understanding and
appreciation of biologically significant pathology findings. The
IDTP consists of four major areas: 1. A-Z Dictionary of Pathology
encompassing all organ systems, together with relevant
non-pathology terms supported by references in "For Further
Reading" sections. 2. Appendix 1: An Overviews of Drug Development,
Nonclinical Safety & Toxicologic Pathology, and
Important/Special Topics. 3. Appendix 2: Diagnostic Criteria of for
Proliferative Proliferative Lesions in Rodents (Rat and Mouse) and
Selected Non-Rodent Laboratory Species containing illustrations
with detailed references and links to source material. 4) Appendix
3: Mini-Atlas of Organ System Anatomy and Histology to help
re-acquaint the non-pathologist safety scientist with many normal
anatomical structures. The editors and contributing scientists
(board-certified veterinary pathologists, board-certified
toxicologists, allied health safety scientists, health regulatory
representatives) have experience from bench-level pathology and
toxicology to managing global preclinical safety units in leading
pharmaceutical companies. They have considerable experience
mentoring pharmaceutical industry project team members, interacting
with industry clinicians and representatives of decision-making
bodies within the industry, as well as with global health
authorities, such as the FDA and EMA. These activities convinced
them of the necessity for and usefulness of the IDTP. As experts in
their field, they have undertaken the hard work of writing and
compiling the information, making the IDTP an exceptional, go-to
reference. *Illustrations Editor: Gregory Argentieri
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