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Lipids and Cellular Membranes in Amyloid Diseases (Hardcover)
Loot Price: R3,875
Discovery Miles 38 750
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Lipids and Cellular Membranes in Amyloid Diseases (Hardcover)
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Addressing one of the biggest riddles in current molecular cell
biology, this ground-breaking monograph builds the case for the
crucial involvement of lipids and membranes in the formation of
amyloid deposits. Tying together recent knowledge from in vitro and
in vivo studes, and built on a sound biophysical and biochemical
foundation, this overview brings the reader up to date with current
models of the interplay between membranes and amyloid
formation.
Required reading for any researcher interested in amyloid formation
and amyloid toxicity, and possible avenues for the prevention or
treatment of neurodegenerative disorders.
From the contents:
* Interactions of Alpha-Synuclein with Lipids
* Interaction of hIAPP and its Precursors with Membranes
* Amyloid Polymorphisms: Structural Basis and Significance in
Biology and Molecular Medicine
* The Role of Lipid Rafts in Alzheimer's Disease
* Alzheimer's Disease as a Membrane-Associated Enzymopathy of
Beta-Amyloid Precursor Protein (APP) Secretases
* Impaired Regulation of Glutamate Receptor Channels and Signaling
Molecules by Beta-Amyloid in Alzheimer's Disease
* Membrane Changes in BSE and Scrapie
* Experimental Approaches and Technical Challenges for Studying
Amyloid-Membrane Interactions
and more
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