Polymers and Nanomaterials for Gene Therapy (Hardcover)

Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy.

General

Imprint:	Woodhead Publishing Ltd
Country of origin:	United Kingdom
Release date:	2016
Editors:	Ravin Narain
Dimensions:	229 x 152 x 20mm (L x W x T)
Format:	Hardcover
Pages:	302
ISBN-13:	978-0-08-100520-0
Categories:	Books > Medicine > Clinical & internal medicine > Gene therapy Books > Professional & Technical > Technology: general issues > Nanotechnology Books > Science & Mathematics > Chemistry > Organic chemistry > Polymer chemistry Promotions
LSN:	0-08-100520-2
Barcode:	9780081005200

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!