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Bacterial Chromatin (Paperback, 2010 ed.)
Loot Price: R5,476
Discovery Miles 54 760
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Bacterial Chromatin (Paperback, 2010 ed.)
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The birth and the development of molecular biology and,
subsequently, of genetic engineering and biotechnology cannot be
separated from the advancements in our knowledge of the genetics,
biochemistry and physiology of bacteria and bacter- phages. Also
most of the tools employed nowadays by biotechnologists are of
bacterial (or bacteriophage) origin and the playground for most of
the DNA manipulations still remains within bacteria. The relative
simplicity of the bacterial cell, the short gene- tion times, the
well defined and inexpensive culturing conditions which
characterize bacteria and the auto-catalytic process whereby a
wealth of in-depth information has been accumulated throughout the
years have significantly contributed to generate a large number of
knowledge-based, reliable and exploitable biological systems. The
subtle relationships between phages and their hosts have produced a
large amount of information and allowed the identification and
characterization of a number of components which play essential
roles in fundamental biological p- cesses such as DNA duplication,
recombination, transcription and translation. For instance, to
remain within the topic of this book, two important players in the
or- nization of the nucleoid, FIS and IHF, have been discovered in
this way. Indeed, it is difficult to find a single fundamental
biological process whose structural and functional aspects are
better known than in bacteria.
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