Connexin Methods and Protocols (Hardcover, 2001 ed.)

Direct cell-cell communication is a common property of multicellular organisms that is achieved through membrane channels which are organized in gap junctions. The protein subunits of these intercellular channels, the connexins, form a multigene family that has been investigated in great detail in recent years. It has now become clear that, in different tissues, connexins speak several languages that control specific cellular functions. This progress has been made possible by the availability of new molecular tools and the improvement of basic techniques for the study of membrane channels, as well as by the use of genetic approaches to study protein function in vivo. More important, connexins have gained visibility because mutations in some connexin genes have been found to be linked to human genetic disorders. Connexin Methods and Protocols presents in detail a collection of te- niques currently used to study the cellular and molecular biology of connexins and their physiological properties. The field of gap junctions and connexin research has always been characterized by a multidisciplinary approach c- bining morphology, biochemistry, biophysics, and cellular and molecular biology. This book provides a series of cutting-edge protocols and includes a large spectrum of practical methods that are available to investigate the fu- tion of connexin channels. Connexin Methods and Protocols is divided into three main parts.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 154
Release date:	December 2000
First published:	2001
Editors:	Roberto Bruzzone • Christian Giaume
Dimensions:	229 x 152 x 30mm (L x W x T)
Format:	Hardcover
Pages:	491
Edition:	2001 ed.
ISBN-13:	978-0-89603-658-1
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Science & Mathematics > Science: general issues > Scientific equipment & techniques, laboratory equipment > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Promotions
LSN:	0-89603-658-8
Barcode:	9780896036581

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