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Drugs Affecting Lipid Metabolism (Paperback, Softcover reprint of the original 1st ed. 1987)
Loot Price: R1,631
Discovery Miles 16 310
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Drugs Affecting Lipid Metabolism (Paperback, Softcover reprint of the original 1st ed. 1987)
Series: Proceedings in Life Sciences
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The recent symposium and the appearance of this new book on Drugs
Affecting Lipid Metabolism take place at a very unusual time for
the development of this area. After the publication and wide
acceptance of the results of the cholestyramine study by the Lipid
Clinics in the USA, showing for the first time a direct association
between drug induced reduction of plasma levels of total and LDL
cholesterol and coronary heart disease in a high risk population,
an unparalleled interest in drugs and other procedures able to
control plasma cholesterol levels has been activated. Two other
significant events occurred during 1986 and 1987: the availability
of compact instruments for the immediate determination of total
cholesterol in plasma or total blood and the developments of new
agents such as the inhibitors of HMG-CoA (hydroxymethyl glutaryl
CoA) reductase and ACAT inhibitors, with potentially great effect
on plasma lipid levels after oral administration. These new
advances, together with the combined efforts of cell biologists and
lipoprotein chemists, have set the pace for an exciting period of
research and clinical applications of diets and drugs af fecting
lipids. This volume, which includes the work of many of the leading
world laboratories, represents an authoritative and up-to-date ap
praisal of the status of the art and a stimulus to future research
at laboratory and clinical level in an area of opportunity for
clinical and preventive medicine."
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