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Meningitis and Encephalitis - Management and Prevention Challenges (Hardcover, 1st ed. 2018)
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Meningitis and Encephalitis - Management and Prevention Challenges (Hardcover, 1st ed. 2018)
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Meningitis and Encephalitis are associated with high rates of
mortality and neurological sequelae. The differential diagnosis
includes a wide spectrum of infectious and non-infectious
etiologies, some requiring urgent therapy for survival. The current
management challenges in patients with meningitis and encephalitis
include a low sensitivity of meningeal signs, overutilization of
unnecessary screening cranial imaging, delays in diagnosis of
urgent treatable causes, a large proportion of unknown etiologies,
low sensitivity of current microbiological techniques especially in
the setting of previous antibiotic therapy, underutilization of
available molecular diagnostic tests, and empiric antibiotic
therapy and hospitalization for viral meningitis cases. Even though
there are published guidelines, compliance with them is not optimal
and physicians do not follow standardized algorithms in their
empirical approach. As meningitis and encephalitis is associated
with high rates of adverse clinical outcomes, prevention, when
feasible is of upmost importance. Adherence to protocols to prevent
health-care associated meningitis and ventriculitis are effective
but compliance with them is not uniformly performed. This book
seeks to improve outcomes for meningitis and encephalitis cases
handled by physicians who may or may not be thoroughly trained for
these challenges. The text introduces the current guidelines but
also discusses the gaps that leave clinicians struggling to
implement the most appropriate approaches for these particular
neurological infections. Each chapter delivers the tools necessary
to identify and adhere to the most appropriate diagnostic
technique, management protocols, and prevention approach for each
situation. All chapters conclude with discourse on future
directions in research and quality improvement. Written by experts
in infectious diseases, the book covers topics that are the most
devastating, including healthcare-acquired infections, autoimmune
encephalitis, and infections as they present in HIV patients.
Meningitis and Encephalitis is a well-rounded resource for all
medical professionals encountering these neurological syndromes,
including infectious disease specialists, neurologists, primary
care physicians, and immunologists.
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