Kruppel-like factors (KLFs) are attracting great attention
across a wide spectrum of biological sciences and medicine because
of their remarkable biological potency and the diversity of roles
they play in the physiological and pathological changes of cells
and tissues. This book is a comprehensive compendium of the latest
research on the molecular mechanisms of KLFs, describing their
roles in transcriptional regulation, cellular differentiation and
development, the pathogenesis of the liver and cardiovascular
systems and cancer, and generation of ES cells and iPS cells. As
the only concise treatise written to date by leading experts in the
field, it serves as an authoritative review of this family of
molecules and is an essential reference for all who are interested
in KLFs. The book also explores the potential of KLFs as targets
for novel therapeutics and diagnostics, and will be invaluable in
those fields.
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