This is a timely collection of important biomedical applications
for a set of separation/characterization techniques that are
rapidly gaining popularity due to their wide dynamic range, high
resolution, and ability to function in most commonly used solvent
systems. Importantly, the field-flow fractionation (FFF) technique
has recently emerged as a prominent complement to size exclusion
chromatography for protein pharmaceuticals. Fractionation with FFF
is gentle and preserves protein structural integrity better than
existing alternatives. In the present text, different chapters are
written by experts in their respective field of application, who
offer comparisons between the FFF techniques and other methods for
characterizing their special focus material. Practical guide-lines
for successful implementation, such as choice of operating
conditions, are offered in conjunction with each application. In
addition to new instrumentation and approaches that address
important current topics, readers are provided with an overall
sense of prior (but timeless) major developments that may be
overlooked in literature searches.
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