The concept of cancer stem cells has great clinical implications.
This is due to the fact that small subpopulations of these cells
have been identified in a variety of neoplastic conditions ranging
from solid tumors to liquid malignancies. Although there are some
huge gaps in our current understanding of the role played by cancer
stem cells in cancer biology, a growing body of evidence provides
strong support for the principal functions of these cells in
tumorigenesis. This has represented the potential of cancer stem
cells in the development of novel and innovative tools for the
treatment of metastatic tumors. This book aims to offer a broad
framework for obtaining insight into the state-of-the-art knowledge
on cancer stem cell biology and highlight the therapeutic
implications of these cells in the future of clinical oncology.
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