Statistical Mechanics, Protein Structure, and Protein Substrate Interactions (Paperback, Softcover reprint of the original 1st ed. 1994)

A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	NATO Science Series B:, 325
Release date:	June 2013
First published:	1994
Editors:	Sebastian Doniach
Dimensions:	235 x 155 x 21mm (L x W x T)
Format:	Paperback
Pages:	406
Edition:	Softcover reprint of the original 1st ed. 1994
ISBN-13:	978-1-4899-1351-7
Categories:	Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > Animal physiology Promotions
LSN:	1-4899-1351-3
Barcode:	9781489913517

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!