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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Handbook of Mitochondrial Dysfunction (Hardcover)
Loot Price: R5,020
Discovery Miles 50 200
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Handbook of Mitochondrial Dysfunction (Hardcover)
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Mitochondria produce the chemical energy necessary for eukaryotic
cell functions; hence mitochondria are an essential component of
health, playing roles in both disease and aging. More than 80 human
diseases and syndromes are associated with mitochondrial
dysfunction; this book focuses upon diseases linked to these
ubiquitous organelles. Accumulation of mitochondrial DNA damage
results in mitochondrial dysfunction through two main pathways.
Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre
syndrome and Pearson syndrome. Mutation in chromosomal DNA causes
diseases such as Parkinson's disease and schizophrenia. These and
many other diseases are reviewed in this book. Key Features
Presents the detailed structure of mitochondria, mitochondrial
function, roles of oxidants and antioxidants in mitochondrial
dysfunction. Includes summary of both causes and effects of these
diseases. Discusses current and potential future therapies for
mitochondrial dysfunction diseases Explores a wide variety of
diseases caused by dysfunctional mitochondria.
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