Toxicology of the Gastrointestinal Tract focuses on the specifics
of the mechanisms and adverse effects of xenobiotic agents and
pharmaceuticals on the structure and function of the GI tract. The
book focuses on a number of specific areas of intestinal research.
Beginning with the well-recognized and major functions of nutrient
absorption and its role as a protective barrier, the text
elaborates on the expanding body of knowledge that relates to the
intestines as a major metabolic and immunologic organ involved in
the synthesis and degradation of both natural and foreign
substances. It includes an overview of the function and dysfunction
of the human absorptive process and the effects of microbial flora
on these processes, as well as specific classes of toxicants that
target the GI tract. The international panel of contributors
presents a critical appraisal of the interactions of chemicals and
drugs with the gastrointestinal system and the experimental methods
and regions of research on which to focus future efforts.
Providing a complete and multidisciplinary overview of the
gastrointestinal system both in health and as it is involved in the
toxicity of exogenous agents, Toxicology of the Gastrointestinal
Tract brings together the current and growing knowledge of this
critical organ system in a single volume.
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