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Functional Molecules from Natural Sources (Hardcover, Edition.)
Loot Price: R3,620
Discovery Miles 36 200
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Functional Molecules from Natural Sources (Hardcover, Edition.)
Series: Special Publications
Expected to ship within 12 - 17 working days
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Naturally occurring compounds, or natural products, have been and
continue to be an important source of commercially successful
products and leads in the pharmaceutical, agrochemical and
nutritional sectors. The conference Functional Molecules from
Natural Sources, which was held at Magdalen College, Oxford in July
2009, set out to highlight current trends, challenges and successes
in the exploitation of natural products from microbial, plant and
marine sources. This book is based on the proceedings of the
conference and comprises modern and emerging perspectives on
natural product utilization and improved strategies for their
exploitation. Several case studies on important natural product
leads, or functional molecules, are presented with the strategy for
their development. These detail new medical applications in the use
of familiar natural molecules and advances in the understanding and
manipulation of natural product biosynthesis at the genetic level.
Highlights include an authoritative review of the entire field of
natural anticancer agents emphasising those currently in clinical
development, an account of the optimisation of the pleuromutilin
antibiotic template for human use and a comprehensive description
of the research programme that resulted in the discovery of
platensimycin. Articles on biosynthesis include studies of the
antibiotics of Streptomyces coelicolor A3(2), the anthrax
siderophore petrobactin and the modification of oxidation and
glycosylation events in the biosynthesis of mithramycins. Written
by leading industrial and academic practitioners from each sector,
the book offers authoritative updates on new approaches to the use
of naturally occurring compounds within the pharmaceutical,
nutraceutical and agrochemical industries.
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