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PAS Proteins: Regulators and Sensors of Development and Physiology (Paperback, Softcover reprint of the original 1st ed. 2003)
Loot Price: R3,016
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PAS Proteins: Regulators and Sensors of Development and Physiology (Paperback, Softcover reprint of the original 1st ed. 2003)
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PAS proteins control numerous physiological and developmental
events, and span phylogeny from bacteria to man. Bacterial and
plant PAS proteins act as sensors of environmental stimuli,
including light, oxygen, and energy status. Not surprising, given
these roles, there is intense investigation of the roles of
bHLH-PAS proteins in issues of human health including: (1) cancer
induction, (2) cancer growth and vascularity, (3) birth defects,
including Down syndrome, (4) appetite control and obesity, (5)
sleep rhythm disorders, and (6) mental health disorders such as
social interactions and learning. PAS proteins encompass many
fields of biology, and scientists who work in these fields
(circadian rhythms, oxygen regulation, toxin metabolism, bacterial
sensors, and development) are an audience, particularly those who
actively work on PAS proteins and researchers interested in
transcriptional control, signal transduction, and evolution.
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