Neuroblastoma - mIBG in its Diagnosis and Management (Paperback, Softcover reprint of the original 1st ed. 1989)

Neuroblastoma is the third most common malignancy of childhood. accounting for 8% of all cancers in patients under 15 years of age. In the majority of cases. by the time neuroblastoma is diagnosed. it has already spread from its site of origin to involve distant sites. Approximately 90% of cases of neuroblastoma can be diagnosed by a combination of techniques including detection of specific tumour markers in the urine. histopathological and immunocytological assessment of involved bone marrow and the 'characteristic' appearances of tumours dem- onstrated by computerised tomography and ultrasonography. However. despite this plethora of techniques. up to. 10% of cases of neuroblastoma are still difficult to diagnose and rely on excisional biopsy of a site of disease. It was against this background that the scintigraphic localisation of neuroblastoma with the radiolabelled guanethidine analogue. mIBG. became available. With mIBG scintigraphy it is now possible to demonstrate the presence of neuro- blastoma (and related tumours) at the primary site. soft tissue sites. in the bone marrow and in cortical bone. in a single investigation. The success of mIBG scintigraphy depends on many factors including the choice of isotope for labelling the mIBG. the equipment used to carry out the procedure. and the manipulation and interpretation of the information obtained. At the Royal Marsden Hospital we have performed over 100 mIBG studies in children. and our advice has frequently been sought by other centres who are. or intend to become.

General

Imprint:	Springer London
Country of origin:	United Kingdom
Release date:	December 2011
First published:	1989
Assisted by:	Sue L. Fielding
Authors:	Judy S.E. Moyes
Assisted by:	Maggie A. Flower
Authors:	V. Ralph McCready • Ann C. Fullbrook
Assisted by:	B. G. Tyrwhitt-Drake
Dimensions:	280 x 210 x 9mm (L x W x T)
Format:	Paperback
Pages:	168
Edition:	Softcover reprint of the original 1st ed. 1989
ISBN-13:	978-1-4471-1676-9
Categories:	Books > Medicine > Other branches of medicine > Nuclear medicine Books > Medicine > Clinical & internal medicine > Paediatric medicine > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > Radiotherapy Promotions
LSN:	1-4471-1676-3
Barcode:	9781447116769

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