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Transgenesis and Secondary Metabolism (Hardcover, 1st ed. 2017)
Loot Price: R5,973
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Transgenesis and Secondary Metabolism (Hardcover, 1st ed. 2017)
Series: Reference Series in Phytochemistry
Expected to ship within 10 - 15 working days
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This handbook provides comprehensive reference information on the
efficient production of secondary metabolites from plants by
transgenesis and other genetic manipulation strategies. It reviews
and summarizes selected important case studies in genetic methods
applied to enhance the production of a given metabolite or a group
of related or derived compounds. Readers will find reference
information on a multitude of techniques and methods, including
traditional breeding and screening; over-expression of genes
encoding key enzymes; functional genomics approaches; metabolic
engineering of the relevant biosynthetic pathways; indirect genetic
approaches to improve metabolite production, including
Agrobacterium mediated transformations. Furthermore, combinatorial
biochemistry approaches to engineer secondary metabolic pathways
are summarized, which can offer access to new structures or to the
design of novel compounds. Since many commercially valuable
substances are still extracted from plants, being largely
inaccessible to efficient modern laboratory synthesis methods, this
book provides a valuable resource of information for
biotechnological approaches that can help to find alternative and
more efficient methods for the production of natural secondary
metabolites. Thus adjusted production methods, with the help of
tailored plant systems, can potentially help to release the stress
on plants, which are currently suffering from extensive human
harvesting, and to conserve global biodiversity. Readers will find
comprehensive reference information on plant genetic manipulation
toward more efficient synthesis, accumulation and production of
target secondary metabolites. The handbook will appeal to
researchers and professionals, but also graduate students and
scholars working in the fields of biotechnology, genetic
engineering, medicinal plant research, pharmacy, and
phytochemistry.
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