Gastrointestinal diseases present a considerable problem in human
medicine in terms of both morbidity and mortality. The aim of this
book is to cover the different immunological disorders of the gut
with special reference to immunopathological and protective
mechanisms. It will be of general interest to clinicians,
scientists and students concerned with the gastrointestinal tract.
Topics covered include: the current status of research into
toxin-secreting pathogens, Campylobacter, Giardia and HIV; the
immunological features of idiopathic inflammatory gut diseases such
as Crohn's disease and intractable diarrhoea; the genesis of the
flat mucosa; the iatrogenic diseases of the gut such as
graft-versus-host disease and small bowel allografts; the immune
mechanisms and lesions in the gut of patients with parasitic
nematode infections (very important in the tropics). Basic
background on the immune apparatus in the intestine is also
discussed, as are the effects of inflammation on intestinal
permeability.
General
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