The discovery of adult neurogenesis caused a paradigm shift in
the neurosciences. For more than 100 years, it was believed that
adult neurons do not regenerate. Joseph Altman and Fernando
Nottebohm found proof to the contrary and changed the course of
history. Their research, included here, provides the foundations of
the field. Today, adult neurogenesis is a rapidly expanding
discipline applicable to the study of brain development and
diseases, learning and memory, aging, and neuropsychiatric
disorders. With multiple authors, the 27 chapters of this book
contain the latest work in two volumes. The first presents the
basic biology of adult neurogenesis in non-mammalian vertebrates
and in the mammalian hippocampus and olfactory bulb, and the second
discusses clinical implications and delves into adult neurogenesis
and brain injury as well as neurodegenerative and neuropsychiatric
pathologies. With details of the anatomy, physiology, and molecular
biology of the two neurogenic brain regions, this book provides
indispensable knowledge for many areas of neuroscience and for
experimental and clinical applications of adult neurogenesis to
brain therapy.
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