This book will cover both the evidence for biofilms in many
chronic bacterial infections as well as the problems facing these
infections such as diagnostics and treatment regimes. A still
increasing interest and emphasis on the sessile bacterial lifestyle
biofilms has been seen since it was realized that that less than
0.1% of the total microbial biomass lives in the planktonic mode of
growth. The term was coined in 1978 by Costerton et al. who defined
the term biofilm for the first time.In 1993 the American Society
for Microbiology (ASM) recognised that the biofilmmode of growth
was relevant to microbiology. Lately many articles have been
published on the clinical implications of bacterial biofilms. Both
original articles and reviews concerning the biofilm problem are
available.
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