Complex Systems Science in Biomedicine
Thomas S. Deisboeck and J. Yasha Kresh
Complex Systems Science in Biomedicine covers the emerging field
of systems science involving the application of physics,
mathematics, engineering and computational methods and techniques
to the study of biomedicine including nonlinear dynamics at the
molecular, cellular, multi-cellular tissue, and organismic level.
With all chapters helmed by leading scientists in the field,
Complex Systems Science in Biomedicine's goal is to offer its
audience a timely compendium of the ongoing research directed to
the understanding of biological processes as whole systems instead
of as isolated component parts.
In Parts I & II, Complex Systems Science in Biomedicine
provides a general systems thinking perspective and presents some
of the fundamental theoretical underpinnings of this rapidly
emerging field. Part III then follows with a multi-scaled approach,
spanning from the molecular to macroscopic level, exemplified by
studying such diverse areas as molecular networks and developmental
processes, the immune and nervous systems, the heart, cancer and
multi-organ failure. The volume concludes with Part IV that
addresses methods and techniques driven in design and development
by this new understanding of biomedical science.
Key Topics Include:
a [ Historic Perspectives of General Systems Thinking
a [ Fundamental Methods and Techniques for Studying Complex
Dynamical Systems
a [ Applications from Molecular Networks to Disease Processes
a [ Enabling Technologies for Exploration of Systems in the Life
Sciences
Complex Systems Science in Biomedicine is essential reading for
experimental, theoretical, and interdisciplinary scientists working
in the biomedical research field interested in a comprehensive
overview of this rapidly emerging field.
About the Editors:
Thomas S. Deisboeck is currently Assistant Professor of Radiology
at Massachusetts General Hospital and Harvard Medical School in
Boston. An expert in interdisciplinary cancer modeling, Dr.
Deisboeck is Director of the Complex Biosystems Modeling Laboratory
which is part of the Harvard-MIT Martinos Center for Biomedical
Imaging.
J. Yasha Kresh is currently Professor of Cardiothoracic Surgery
and Research Director, Professor of Medicine and Director of
Cardiovascular Biophysics at the Drexel University College of
Medicine. An expert in dynamical systems, he holds appointments in
the School of Biomedical Engineering and Health Systems, Dept. of
Mechanical Engineering and Molecular Pathobiology Program. Prof.
Kresh is Fellow of the American College of Cardiology, American
Heart Association, Biomedical Engineering Society, American
Institute for Medical and Biological Engineering.
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